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TTC3 Antikörper (AA 251-350)

TTC3 Reaktivität: Maus, Ratte IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6989022
  • Target Alle TTC3 Antikörper anzeigen
    TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
    Bindungsspezifität
    • 2
    • 2
    • 1
    • 1
    AA 251-350
    Reaktivität
    • 5
    • 3
    • 2
    Maus, Ratte
    Wirt
    • 5
    • 2
    Kaninchen
    Klonalität
    • 6
    • 1
    Polyklonal
    Konjugat
    • 5
    • 1
    • 1
    Dieser TTC3 Antikörper ist unkonjugiert
    Applikation
    • 4
    • 3
    • 2
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human RNF105
    Isotyp
    IgG
    Top Product
    Discover our top product TTC3 Primärantikörper
  • Applikationshinweise
    IHC-P 1:200-400
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))
    Andere Bezeichnung
    RNF105 (TTC3 Produkte)
    Synonyme
    DCRR1 antikoerper, RNF105 antikoerper, TPRDIII antikoerper, 2610202A04Rik antikoerper, AA409221 antikoerper, D16Ium21 antikoerper, D16Ium21e antikoerper, TPRD antikoerper, mKIAA4119 antikoerper, TTC3 antikoerper, tetratricopeptide repeat domain 3 antikoerper, E3 ubiquitin-protein ligase TTC3 antikoerper, TTC3 antikoerper, Ttc3 antikoerper, LOC100562480 antikoerper
    Hintergrund

    Synonyms: DCRR1, E3 ubiquitin protein ligase TTC3, E3 ubiquitin-protein ligase TTC3, Protein DCRR1, RING finger protein 105,Tetratricopeptide repeat protein 3 (TPR repeat protein D), Tetratricopeptide repeat protein 3, TPR repeat protein 3, TPR repeat protein D, TPRD, TPRDI, TPRDII, TPRDIII, TTC3, TTC3_HUMAN.

    Background: E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.

    Gen-ID
    7267
    UniProt
    P53804
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