TTC3 Antikörper (N-Term)

Produktnummer ABIN347721

Produktdetails anti-TTC3 Antikörper

Target: TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TTC3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (IF)

Spezifität: Reacts with human E3 ubiquitin-protein ligase TTC3

Aufreinigung: Antiserum

Immunogen: Synthetic peptide derived from Cter domain of human TTC3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise:

Working dilution: Optimal dilution should be determined by the end user.
The following are guidelines only :
IF(1:100 - 1:500) WB(1:500 - 1:5000)

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Must be reconstituted in distilled water.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Haltbarkeit: 24 months

Details zu TTC3

Target: TTC3 (Tetratricopeptide Repeat Domain 3 (TTC3))

Andere Bezeichnung: E3 ubiquitin-protein ligase TTC3 (TTC3 Produkte)

Hintergrund: E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation, its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.

UniProt: P53804