BTBD12 Antikörper (AA 171-270) (HRP)

Produktnummer ABIN6987708

Dieses Anti-BTBD12-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von BTBD12 in IHC (p), ELISA und IHC (fro). Geeignet für Maus.

Kurzübersicht für BTBD12 Antikörper (AA 171-270) (HRP) (ABIN6987708)

Target: BTBD12 (BTB (POZ) Domain Containing 12 (BTBD12))

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BTBD12 Antikörper ist konjugiert mit HRP

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-BTBD12 Antikörper (HRP)

Bindungsspezifität: AA 171-270

Kreuzreaktivität: Maus

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SLX4/BTBD12

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu BTBD12

Target: BTBD12 (BTB (POZ) Domain Containing 12 (BTBD12))

Andere Bezeichnung: SLX4

Hintergrund:

Synonyms: BTB (POZ) domain containing 12, BTB/POZ domain-containing protein 12, BTBD12, FANCP, KIAA1784, KIAA1987, MUS312, SLX 4, slx4, SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae), SLX4_HUMAN, Structure-specific endonuclease subunit slx4.

Background: This gene encodes a structure-specific endonuclease subunit. The encoded protein contains a central BTB domain and it forms a multiprotein complex with the ERCC4(XPF)-ERCC1, MUS81-EME1, and SLX1 endonucleases, and also associates with MSH2/MSH3 mismatch repair complex, telomere binding complex TERF2(TRF2)-TERF2IP(RAP1), the protein kinase PLK1 and the uncharacterized protein C20orf94. The multiprotein complex is required for repair of specific types of DNA lesions and is critical for cellular responses to replication fork failure. The encoded protein acts as a docking platform for the assembly of multiple structure-specific endonucleases.[provided by RefSeq, Jan 2011]

Gen-ID: 84464

UniProt: Q8IY92

Pathways: DNA Reparatur