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ALKBH5 Antikörper (AA 1-100) (HRP)

ALKBH5 Reaktivität: Maus, Ratte ELISA, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal HRP
Produktnummer ABIN6987669
  • Target Alle ALKBH5 Antikörper anzeigen
    ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
    Bindungsspezifität
    • 14
    • 7
    • 7
    • 6
    • 6
    • 2
    • 1
    AA 1-100
    Reaktivität
    • 26
    • 23
    • 16
    Maus, Ratte
    Wirt
    • 38
    • 2
    Kaninchen
    Klonalität
    • 40
    Polyklonal
    Konjugat
    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ALKBH5 Antikörper ist konjugiert mit HRP
    Applikation
    • 19
    • 17
    • 13
    • 13
    • 3
    • 2
    • 1
    • 1
    • 1
    ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Cow,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human ALKBH5
    Isotyp
    IgG
    Top Product
    Discover our top product ALKBH5 Primärantikörper
  • Applikationshinweise
    IHC-P 1:200-400
    IHC-F 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    ALKBH5 (AlkB, Alkylation Repair Homolog 5 (ALKBH5))
    Andere Bezeichnung
    ALKBH5 (ALKBH5 Produkte)
    Synonyme
    RGD1309496 antikoerper, ABH5 antikoerper, OFOXD antikoerper, OFOXD1 antikoerper, AW050020 antikoerper, AW215868 antikoerper, Abh5 antikoerper, E130207K11 antikoerper, Ofoxd antikoerper, alkB homolog 5, RNA demethylase antikoerper, alkB homolog 5, RNA demethylase L homeolog antikoerper, Alkbh5 antikoerper, alkbh5.L antikoerper, ALKBH5 antikoerper
    Hintergrund

    Synonyms: ABH5, AlkB, alkylation repair homolog 5 (E. coli), AlkB, alkylation repair homolog 5, Alkylated DNA repair protein alkB homolog 5, Alpha ketoglutarate dependent dioxygenase alkB homolog 5, OFOXD, OFOXD1, Oxoglutarate and iron-dependent oxygenase domain containing, Probable alpha ketoglutarate dependent dioxygenase ABH5, RNA demethylase ALKBH5.

    Background: Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A)RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:23177736, PubMed:24778178,PubMed:24616105, PubMed:24489119). Can also demethylate N(6)-methyladenosine in single-stranded DNA (in vitro)(PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron (PubMed:21264265, PubMed:23177736, PubMed:24778178,PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export (PubMed:23177736). Required for spermatogenesis (By similarity).

    Gen-ID
    54890
    UniProt
    Q6P6C2
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