Calsequestrin Antikörper (AA 1-100) (Cy5.5)

Produktnummer ABIN6985430

Der Kaninchen Polyklonal Anti-Calsequestrin-Antikörper wurde für WB, IF (cc) und IF (p) validiert. Er ist geeignet, Calsequestrin in Proben von Human zu detektieren.

Kurzübersicht für Calsequestrin Antikörper (AA 1-100) (Cy5.5) (ABIN6985430)

Target: Calsequestrin (CASQ1) (Calsequestrin 1 (CASQ1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Calsequestrin Antikörper ist konjugiert mit Cy5.5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-Calsequestrin Antikörper (Cy5.5)

Bindungsspezifität: AA 1-100

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Calsequestrin

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Calsequestrin

Target: Calsequestrin (CASQ1) (Calsequestrin 1 (CASQ1))

Andere Bezeichnung: Calsequestrin-1

Hintergrund:

Synonyms: CASQ, Calsequestrin 1, Calsequestrin 1 fast twitch skeletal muscle, Calsequestrin skeletal muscle isoform, CASQ 1, CASQ1, PDIB1, Skeletal muscle calsequestrin 1, Calmitine.

Background: The sarcoplasmic reticulum (SR) is, in part, responsible for maintaining the level of intracellular calcium in cardiac and skeletal muscle by storing and releasing calcium. Several intralumenal SR calcium binding proteins have been identified, the most prominent of these is calsequestrin. Calsequstrin is a calcium binding protein known to sequester calcium accumulated in the sarcoplasmic reticulum of muscle cells during relaxation and is found discretely localized to the junctional and corbular (terminal cisternae) SR. Calsequestrin functions to localize calcium near the junctional face of the terminal cisternae from which calcium can be released into the cytosol via the ryanodine receptor. This protein is highly acidic and has a large capacity and moderate to low affinity for calcium.

Gen-ID: 844

UniProt: P31415