SMAD9 Antikörper (AA 351-450) (Cy3)
Kurzübersicht für SMAD9 Antikörper (AA 351-450) (Cy3) (ABIN6983972)
Target
Alle SMAD9 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 351-450
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Kreuzreaktivität
- Human, Maus, Ratte, Zebrafisch (Danio rerio)
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human SMAD8
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- SMAD9 (SMAD Family Member 9 (SMAD9))
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Andere Bezeichnung
- SMAD8
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Hintergrund
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Synonyms: AI528653 , BSP 1 , BSP1 , DKFZp781C1895 , DKFZp781O1323 , Dwarfin A , Dwf A , DwfA , Dwfc , hSMAD1 , hSmad5 , JV 41 , JV4 1 , JV41 , JV5 1 , MAD (mothers against decapentaplegic, Drosophila) homolog 1 , MAD (mothers against decapentaplegic, Drosophila) homolog 9 , MAD homolog 1 , MAD homolog 9 , MAD homolog1 (mothers against decapentaplegic, Drosophila) ,
Background: Sphingomyelin synthases synthesize sphingolipids through transfer of a phosphatidyl head group on to the primary hydroxyl of ceramide. SAMD8 is an endoplasmic reticulum (ER) transferase that has no sphingomyelin synthase activity but can convert phosphatidylethanolamine (PE) and ceramide to ceramide phosphoethanolamine (CPE) albeit with low product yield. Appears to operate as a ceramide sensor to control ceramide homeostasis in the endoplasmic reticulum rather than a converter of ceramides. Seems to be critical for the integrity of the early secretory pathway
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Gen-ID
- 142891
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UniProt
- Q96LT4
Target
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