Metabotropic Glutamate Receptor 5 Antikörper (AA 431-530) (Cy3)

Produktnummer ABIN6983579

Der Kaninchen Polyklonal Anti-Metabotropic Glutamate Receptor 5-Antikörper wurde für WB und FACS validiert. Er ist geeignet, Metabotropic Glutamate Receptor 5 in Proben von Ratte und Maus zu detektieren.

Kurzübersicht für Metabotropic Glutamate Receptor 5 Antikörper (AA 431-530) (Cy3) (ABIN6983579)

Target: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Metabotropic Glutamate Receptor 5 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Flow Cytometry (FACS)

Produktdetails anti-Metabotropic Glutamate Receptor 5 Antikörper (Cy3)

Bindungsspezifität: AA 431-530

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Sheep,Horse,Chicken,Monkey

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human MGLUR5

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM 1:20-100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu Metabotropic Glutamate Receptor 5

Target: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Andere Bezeichnung: MGLUR5

Hintergrund:

Synonyms: MGLUR5B, Glutamate receptor metabotropic 5, GPRC1E, GRM 5, GRM5, Metabotropic glutamate receptor 5, mGlu5, mGluR5, mGluR5a, mGluR5b, Metabotropic glutamate receptor 5 variant F, Metabotropic Glutamate Receptor 5b, Metabotropic glutamate receptor 5 variant G, Metabotropic glutamate receptor 5 variant H, PPP1R86, GRM5_HUMAN,

Background: Glutamate receptors constitute the principal excitatory neurotransmitter receptors in brain. Two classes of glutamate receptors exist: Ionotropic receptors, and metabotropic receptors (mGluRs). Metabotropic Glutamate Receptor 5b (GRM5) activity is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The metabotropic glutamate receptor type 5 (mGlu5) is expressed in two splice variants, mGlu5a and mGlu5b, which differ in that mGlu5b has a 33-amino acid insert in the intracellular C-terminal domain. This receptor subtype is highly regulated, with higher levels found in developing animals.

Gen-ID: 2915

UniProt: P41594

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity