Caspase 1 (p10) Antikörper (AA 301-380) (Biotin)
Kurzübersicht für Caspase 1 (p10) Antikörper (AA 301-380) (Biotin) (ABIN6982756)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 301-380
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Kreuzreaktivität
- Human, Ratte
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Homologie
- Mouse
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from mouse Caspase-1 P10
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Isotyp
- IgG
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Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- Caspase 1 (p10) (CASP-1 (p10))
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Andere Bezeichnung
- Caspase-1 P10
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Hintergrund
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Synonyms: caspase-1 isoform alpha p10 subunit, CASP 1, CASP1, Caspase 1 apoptosis related cysteine peptidase, Caspase 1 apoptosis related cysteine protease, Caspase1, ICE, IL 1 beta converting enzyme, IL 1BC, IL1B convertase, IL1BC, IL1BCE, Interleukin 1 beta convertase, Interleukin 1 beta convertase precursor, Interleukin 1 beta converting enzyme. CASP-1, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45, Caspase-1 subunit p10.
Background: Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis.
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Gen-ID
- 834
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UniProt
- P29452
Target
-