Caspase 1 (p10) Antikörper (AA 321-404) (Biotin)

Produktnummer ABIN6982755

Produktdetails anti-Caspase 1 (p10) Antikörper (Biotin)

Target: Caspase 1 (p10) (CASP-1 (p10))

Bindungsspezifität: AA 321-404

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Caspase 1 (p10) Antikörper ist konjugiert mit Biotin

Applikation: Western Blotting (WB), ELISA

Kreuzreaktivität: Human, Maus

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Caspase-1 P10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu Caspase 1 (p10)

Target: Caspase 1 (p10) (CASP-1 (p10))

Andere Bezeichnung: Caspase-1 P10 (CASP-1 (p10) Produkte)

Hintergrund:

Synonyms: caspase-1 isoform alpha p10 subunit, CASP 1, CASP1, Caspase 1 apoptosis related cysteine peptidase, Caspase 1 apoptosis related cysteine protease, Caspase1, ICE, IL 1 beta converting enzyme, IL 1BC, IL1B convertase, IL1BC, IL1BCE, Interleukin 1 beta convertase, Interleukin 1 beta convertase precursor, Interleukin 1 beta converting enzyme. CASP-1, Interleukin-1 beta convertase, IL-1BC, Interleukin-1 beta-converting enzyme, ICE, IL-1 beta-converting enzyme, p45, Caspase-1 subunit p10.,

Background: This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing of this gene results in five transcript variants encoding distinct isoforms. [provided by RefSeq].

Gen-ID: 834

UniProt: P29466