E2F3 Antikörper (AA 91-190) (AbBy Fluor® 680)

Produktnummer ABIN6981297

Dieses Anti-E2F3-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von E2F3 in WB, IF (cc) und IF (p). Geeignet für Maus und Ratte.

Kurzübersicht für E2F3 Antikörper (AA 91-190) (AbBy Fluor® 680) (ABIN6981297)

Target: E2F3

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser E2F3 Antikörper ist konjugiert mit AbBy Fluor® 680

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-E2F3 Antikörper (AbBy Fluor® 680)

Bindungsspezifität: AA 91-190

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human E2F3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu E2F3

Target: E2F3

Hintergrund:

Synonyms: DKFZp686C18211, E2F 3, E2F transcription factor 3, KIAA0075, MGC104598, Transcription factor E2F 3, E2F3_HUMAN, Transcription factor E2F3, E2F-3.

Background: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F2, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner. [provided by RefSeq].

Gen-ID: 1871

UniProt: O00716