NOTCH4 Antikörper (AA 1151-1250) (AbBy Fluor® 594)
Kurzübersicht für NOTCH4 Antikörper (AA 1151-1250) (AbBy Fluor® 594) (ABIN6979675)
Target
Alle NOTCH4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1151-1250
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Kreuzreaktivität
- Maus, Ratte
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Homologie
- Human,Dog,Cow,Sheep,Pig,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human NOTCH4
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- NOTCH4 (Notch 4 (NOTCH4))
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Andere Bezeichnung
- NOTCH4
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Hintergrund
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Synonyms: Notch 4, FLJ16302, hNotch 4, hNotch4, INT 3, INT3, MGC74442, Neurogenic locus notch homolog protein 4, NOTC4_HUMAN, NOTCH 3, NOTCH 4, Notch 4 intracellular domain, Notch homolog 4, NOTCH3, Notch4, NOTCH4 protein, OTTHUMP00000062678.
Background: Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system.
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Gen-ID
- 4855
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UniProt
- Q99466
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Pathways
- Notch Signalweg
Target
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