Ubiquitin Antikörper
Kurzübersicht für Ubiquitin Antikörper (ABIN6972898)
Target
Alle Ubiquitin (Ub) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
-
-
Produktmerkmale
- Ubiquitin is an important signaling protein that is catalytically added to proteins on lysine residues to modify their function. Addition of multiple ubiquitin proteins in a string (poly-ubiquitylation) to proteins signals their destruction by the proteasome. Mono-ubiquitylation of proteins has a much different effect, more in keeping with post-translational modification of proteins by phosphorylation or acetylation. Mono-ubiquitylation is part of a number of signal transduction pathways, including those involving histone proteins and transcriptional regulation. Ubiquitin antibody (mAb) (Clone P4D1) was raised in a Mouse host. It has been validated for use in Western blot, it has been shown to react with Human samples, but it is predicted that it will react with a wide range of sample types.
-
Aufreinigung
- Protein A Chromatography
-
Immunogen
- This Ubiquitin antibody was raised against purified bovine ubiquitin.
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- Optimal working dilution should be determined by the investigator.
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Buffer
- PBS, 30 % glycerol and 0.035 % sodium azide.
-
Konservierungsmittel
- Sodium azide
-
Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
-
-
- Ubiquitin (Ub)
-
Andere Bezeichnung
- Ubiquitin
-
Pathways
- Mitotic G1-G1/S Phases, Ubiquitin Proteasome Pathway
Target
-