SMC3 Antikörper (C-Term)

Produktnummer ABIN6972756

Der Kaninchen Polyklonal Anti-SMC3-Antikörper wurde für WB validiert. Er ist geeignet, SMC3 in Proben von Human zu detektieren.

Kurzübersicht für SMC3 Antikörper (C-Term) (ABIN6972756)

Target: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SMC3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-SMC3 Antikörper

Bindungsspezifität: C-Term

Produktmerkmale: The Structural Maintenance of Chromosomes (SMC) family proteins play critical roles in various nuclear events that require structural changes of chromosomes, including mitotic chromosome organization, DNA recombination and repair and global transcriptional repression. SMC3 is a component of the cohesin complex that plays an essential role during chromatid segregation. SMC3 is also involved in DNA recombination and repair, mitotic chromosome organization and microtubule-mediated intracellular transport. SMC3 is acetylated during replication, which is essential for cohesion, and is phosphorylated by ATM subsequent to DNA double strand breakage. SMC3 is frequently elevated in human colon carcinoma and overexpression of the protein transforms fibroblasts. SMC3 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Aufreinigung: Affinity Purified

Immunogen: This SMC3 antibody was raised against a peptide in the C-terminal region of human SMC3.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu SMC3

Target: SMC3 (Structural Maintenance of Chromosomes 3 (SMC3))

Andere Bezeichnung: SMC3

Molekulargewicht: 150 kDa

NCBI Accession: NP_005436

Pathways: Stem Cell Maintenance