RAR-alpha (AA 420-443) Antikörper

Produktnummer ABIN6972582

Der Maus Monoklonal anti-RAR-alpha Antikörper wird verwendet zum Nachweis von RAR-alpha in Proben von Human und Maus. Er wurde validiert für IHC, SSA und WB.

Kurzübersicht für RAR-alpha (AA 420-443) Antikörper (ABIN6972582)

Target: RAR-alpha

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Immunohistochemistry (IHC), Supershift Assay (SSA), Western Blotting (WB)

Klon: 9alpha-9A6

Produktdetails

Bindungsspezifität: AA 420-443

Produktmerkmale: Retinoic acid receptors (RAR) are nuclear receptors that are activated by both all-trans retinoic acid and 9-cis retinoic acid. There are three retinoic acid receptors (RAR), RAR-a, RAR-b and RAR-g. RAR-a (Nuclear receptor subfamily 1 group B member 1, NR1B1) interacts with NCoA3, NCoA6, NCoA7 and MLL to activate transcription of target genes. Chromosomal aberrations of RAR-a are sometimes involved in Promyelocytic leukemia. RAR-alpha antibody (mAb) (Clone 9a-9A6) was raised in a Mouse host. It has been validated for use in Immunohistochemistry, Supershift and Western blot, it has been shown to react with Human and Mouse samples.

Aufreinigung: Protein A Chromatography

Immunogen: This RAR-a antibody was raised against a recombinant protein corresponding to amino acids 420-443 (the F region) of human RARa.

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in 60 mM Sodium Citrate, 105 mM Tris-HCl, 30 % glycerol, and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Antigendetails

Target: RAR-alpha

Andere Bezeichnung: RAR-α

Molekulargewicht: 52 kDa

NCBI Accession: NP_001138773