RAR-alpha (AA 420-443) Antikörper
Reaktivität: Human, Maus
IHC, SSA, WB
Wirt: Maus
Monoclonal
9alpha-9A6
unconjugated
-
- Target
- RAR-alpha
-
Bindungsspezifität
- AA 420-443
- Reaktivität
- Human, Maus
-
Wirt
- Maus
-
Klonalität
- Monoklonal
-
Konjugat
- Unkonjugiert
- Applikation
- Immunohistochemistry (IHC), Supershift Assay (SSA), Western Blotting (WB)
- Produktmerkmale
- Retinoic acid receptors (RAR) are nuclear receptors that are activated by both all-trans retinoic acid and 9-cis retinoic acid. There are three retinoic acid receptors (RAR), RAR-a, RAR-b and RAR-g. RAR-a (Nuclear receptor subfamily 1 group B member 1, NR1B1) interacts with NCoA3, NCoA6, NCoA7 and MLL to activate transcription of target genes. Chromosomal aberrations of RAR-a are sometimes involved in Promyelocytic leukemia. RAR-alpha antibody (mAb) (Clone 9a-9A6) was raised in a Mouse host. It has been validated for use in Immunohistochemistry, Supershift and Western blot, it has been shown to react with Human and Mouse samples.
- Aufreinigung
- Protein A Chromatography
- Immunogen
- This RAR-a antibody was raised against a recombinant protein corresponding to amino acids 420-443 (the F region) of human RARa.
- Klon
- 9alpha-9A6
- Isotyp
- IgG1 kappa
-
-
- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Buffer
- Purified IgG in 60 mM Sodium Citrate, 105 mM Tris-HCl, 30 % glycerol, and 0.035 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
-
- Target
- RAR-alpha
- Andere Bezeichnung
- RAR-α
- Molekulargewicht
- 52 kDa
- NCBI Accession
- NP_001138773
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