AGO2 Antikörper (AA 1-148)

Produktnummer ABIN6971363

Produktdetails anti-AGO2 Antikörper

Target: AGO2 (Argonaute 2 (AGO2))

Bindungsspezifität: AA 1-148

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser AGO2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Produktmerkmale: Argonaute 2 (Ago2, aka EIF2C2) is a member of the Argonaute family of proteins involved in RNAi mediated gene silencing through siRNA and miRNA effectors. The Argonaute proteins are part of RISC, the RNAi Induced Silencing Complex. Binding of RISC can inhibit mRNA translation and results in the degradation of the mRNA through the action of Ago2-mediated target cleavage. Ago2 antibody (mAb) (Clone 1B1-E2H5) was raised in a Mouse host. It has been validated for use in Immunocytochemistry, Immunofluorescence, Immunoprecipitation and Western blot, it has been shown to react with Human samples.

Aufreinigung: Protein G Chromatography

Immunogen: This Ago2 antibody was raised against a recombinant protein corresponding to amino acids 1-148 of human Ago2.

Klon: 1B1-E2H5

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Purified IgG in 70 mM Tris ( pH 8), 105 mM NaCl, 31 mM glycine, 0.07 mM EDTA, 30 % glycerol and 0.035 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Details zu AGO2

Target: AGO2 (Argonaute 2 (AGO2))

Andere Bezeichnung: Ago2 (AGO2 Produkte)

Molekulargewicht: 100 kDa

NCBI Accession: NP_036286

Pathways: Fc-epsilon Rezeptor Signalübertragung, Regulatorische RNA Pathways, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Ribonucleoprotein Complex Subunit Organization