GM-CSF Antikörper

Produktnummer ABIN6964026

Der Ratte Monoklonal Anti-GM-CSF-Antikörper wurde für Neut validiert. Er ist geeignet, GM-CSF in Proben von Human und Non-Human Primate zu detektieren. Es sind 2+ Publikationen verfügbar.

Kurzübersicht für GM-CSF Antikörper (ABIN6964026)

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Reaktivität: Human, Non-Human Primate

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser GM-CSF Antikörper ist unkonjugiert

Applikation: Neutralization (Neut)

Klon: 23B6

Produktdetails anti-GM-CSF Antikörper

Spezifität: Native and recombinant GM-CSF

Kreuzreaktivität (Details): The antibody cross-reacts with GM-CSF from non-human primates. Cross-reactivity has been tested in ELISA and/or ELISpot.

Aufreinigung: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Recombinant human GM-CSF

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Neutralization of human GM-CSF bioactivity. It is recommended to establish the optimal antibody concentration for the assay system used. The antibody is also suitable for immunoassays.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS free of preservatives

Konservierungsmittel: Without preservative

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Haltbarkeit: 18 months

Referenzen für anti-GM-CSF Antikörper (ABIN6964026)

Scian, Barrionuevo, Giambartolomei, Fossati, Baldi, Delpino: "Granulocyte-macrophage colony-stimulating factor- and tumor necrosis factor alpha-mediated matrix metalloproteinase production by human osteoblasts and monocytes after infection with Brucella abortus." in: Infection and immunity, Vol. 79, Issue 1, pp. 192-202, (2011) (PubMed).

Kelly, Koziol-White, Clay, Liu, Bates, Bertics, Jarjour: "Potential contribution of IL-7 to allergen-induced eosinophilic airway inflammation in asthma." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 3, pp. 1404-10, (2009) (PubMed).

Details zu GM-CSF

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Andere Bezeichnung: GMCSF

Gen-ID: 1437

Pathways: JAK-STAT Signalweg, Cellular Response to Molecule of Bacterial Origin