IL-21 Antikörper (Biotin)

Produktnummer ABIN6963916

Dieses Anti-IL-21-Antikörper ist ein Maus Monoklonal-Antikörper zur Detektion von IL-21 in ELISA und ELISpot. Geeignet für Human und Non-Human Primate. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.

Kurzübersicht für IL-21 Antikörper (Biotin) (ABIN6963916)

Target: IL-21 (IL21) (Interleukin 21 (IL21))

Reaktivität: Human, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-21 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, ELISpot

Klon: MT21-3m

Produktdetails anti-IL-21 Antikörper (Biotin)

Spezifität: Native and recombinant human IL-21

Kreuzreaktivität (Details): The monoclonal antibody cross-reacts with IL-21 from non-human primates. See the Human/NHP cross-reactivity table.

Aufreinigung: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Recombinant human IL-21

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: For quantification of IL-21 in solution e.g. cell culture supernatants using ELISA and for enumeration of IL-21 producing cells using ELISpot. MT21.3m is recommended as detection mAb in combination with coating mAb MT216G . The antibody is also suitable for Western blot.

Kommentare:

Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Haltbarkeit: 18 months

Referenzen für anti-IL-21 Antikörper (Biotin) (ABIN6963916)

Yamamoto, Kitawaki, Sugimoto, Fujita, Kawase, Takaori-Kondo, Kadowaki: "Anti-inflammatory modulation of human myeloid-derived dendritic cell subsets by lenalidomide." in: Immunology letters, Vol. 211, pp. 41-48, (2020) (PubMed).

Amu, Lantto Graham, Bekele, Nasi, Bengtsson, Rethi, Sorial, Meini, Zazzi, Hejdeman, Chiodi: "Dysfunctional phenotypes of CD4+ and CD8+ T cells are comparable in patients initiating ART during early or chronic HIV-1 infection." in: Medicine, Vol. 95, Issue 23, pp. e3738, (2017) (PubMed).

Li, Sullivan, Rouphael, Yu, Banton, Maddur, McCausland, Chiu, Canniff, Dubey, Liu, Tran, Hagan, Duraisingham, Wieland, Mehta, Whitaker, Subramaniam, Jones, Sette, Vora, Weinberg, Mulligan, Nakaya et al.: "Metabolic Phenotypes of Response to Vaccination in Humans. ..." in: Cell, Vol. 169, Issue 5, pp. 862-877.e17, (2017) (PubMed).

Huang, Ehrnfelt, Paulie, Zuber, Ahlborg: "ELISpot and ELISA analyses of human IL-21-secreting cells: Impact of blocking IL-21 interaction with cellular receptors." in: Journal of immunological methods, Vol. 417, pp. 60-66, (2015) (PubMed).

Details zu IL-21

Target: IL-21 (IL21) (Interleukin 21 (IL21))

Andere Bezeichnung: IL21

Gen-ID: 59067

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response