GM-CSF Antikörper (Biotin)

Produktnummer ABIN6963889

Dieses Anti-GM-CSF-Antikörper ist ein Ratte Monoklonal-Antikörper zur Detektion von GM-CSF in ELISA und ELISpot. Geeignet für Human und Non-Human Primate. Dieses Primary Antibody wurde in 4+ Publikationen zitiert.

Kurzübersicht für GM-CSF Antikörper (Biotin) (ABIN6963889)

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Reaktivität: Human, Non-Human Primate

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser GM-CSF Antikörper ist konjugiert mit Biotin

Applikation: ELISA, ELISpot

Klon: 23B6

Produktdetails anti-GM-CSF Antikörper (Biotin)

Spezifität: Native and recombinant GM-CSF

Kreuzreaktivität (Details): The monoclonal antibody cross-reacts with GM-CSF from non-human primates.

Produktmerkmale: This monoclonal antibody enables specific detection of human GM-CSF in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples

Aufreinigung: Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant human GM-CSF

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

ABIN6963889, ABIN7489152 and ABIN6964026 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAb ABIN6963888 and ABIN7489151 .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Haltbarkeit: 18 months

Referenzen für anti-GM-CSF Antikörper (Biotin) (ABIN6963889)

Ammitzbøll, Börnsen, Romme Christensen, Ratzer, Romme Nielsen, Søndergaard, von Essen, Sellebjerg: "Smoking reduces circulating CD26hiCD161hi MAIT cells in healthy individuals and patients with multiple sclerosis." in: Journal of leukocyte biology, Vol. 101, Issue 5, pp. 1211-1220, (2017) (PubMed).

Myers, Cooper, Kem, Stavrakis, Kosanke, Shevach, Fairweather, Stoner, Cox, Cunningham: "Cardiac myosin-Th17 responses promote heart failure in human myocarditis." in: JCI insight, Vol. 1, Issue 9, (2016) (PubMed).

Morita, Yamamoto, Suzuki, Mori, Igarashi, Sugita: "Molecular requirements for T cell recognition of N-myristoylated peptides derived from the simian immunodeficiency virus Nef protein." in: Journal of virology, Vol. 87, Issue 1, pp. 482-8, (2013) (PubMed).

Ruiss, Jochum, Wanner, Reisbach, Hammerschmidt, Zeidler: "A virus-like particle-based Epstein-Barr virus vaccine." in: Journal of virology, Vol. 85, Issue 24, pp. 13105-13, (2012) (PubMed).

Details zu GM-CSF

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Andere Bezeichnung: GMCSF

Gen-ID: 1437

Pathways: JAK-STAT Signalweg, Cellular Response to Molecule of Bacterial Origin