GM-CSF Antikörper

Produktnummer ABIN6963888

Der Ratte Monoklonal Anti-GM-CSF-Antikörper wurde für ELISA und ELISpot validiert. Er ist geeignet, GM-CSF in Proben von Human und Non-Human Primate zu detektieren. Es sind 5+ Publikationen verfügbar.

Kurzübersicht für GM-CSF Antikörper (ABIN6963888)

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Reaktivität: Human, Non-Human Primate

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser GM-CSF Antikörper ist unkonjugiert

Applikation: ELISA, ELISpot

Klon: 21C11

Produktdetails anti-GM-CSF Antikörper

Spezifität: Native and recombinant GM-CSF

Kreuzreaktivität (Details): The monoclonal antibody cross-reacts with GM-CSF from non-human primates.

Produktmerkmale: This monoclonal antibody enables specific detection of human GM-CSF in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples

Aufreinigung: Purified from in vitro cultures by protein G affinity chromatography.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant human GM-CSF

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

ABIN6963888 and ABIN7489151 is recommended as capture mAb in ELISpot, FluoroSpot, and ELISA in combination with detection mAb ABIN6963889, ABIN7489152 and ABIN6964026 .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Haltbarkeit: 18 months

Referenzen für anti-GM-CSF Antikörper (ABIN6963888)

Jarrett, Salio, Lloyd-Lavery, Subramaniam, Bourgeois, Archer, Cheung, Hardman, Chandler, Salimi, Gutowska-Owsiak, de la Serna, Fallon, Jolin, Mckenzie, Dziembowski, Podobas, Bal, Johnson, Moody et al.: "Filaggrin inhibits generation of CD1a neolipid antigens by house dust mite-derived phospholipase. ..." in: Science translational medicine, Vol. 8, Issue 325, pp. 325ra18, (2016) (PubMed).

Myers, Cooper, Kem, Stavrakis, Kosanke, Shevach, Fairweather, Stoner, Cox, Cunningham: "Cardiac myosin-Th17 responses promote heart failure in human myocarditis." in: JCI insight, Vol. 1, Issue 9, (2016) (PubMed).

Morita, Yamamoto, Suzuki, Mori, Igarashi, Sugita: "Molecular requirements for T cell recognition of N-myristoylated peptides derived from the simian immunodeficiency virus Nef protein." in: Journal of virology, Vol. 87, Issue 1, pp. 482-8, (2013) (PubMed).

Gille-Johnson, Smedman, Gudmundsdotter, Somell, Nihlmark, Paulie, Andersson, Gårdlund: "Circulating monocytes are not the major source of plasma cytokines in patients with sepsis." in: Shock (Augusta, Ga.), Vol. 38, Issue 6, pp. 577-83, (2013) (PubMed).

Mäkitalo, Andersson, Areström, Karlén, Villinger, Ansari, Paulie, Thorstensson, Ahlborg: "ELISpot and ELISA analysis of spontaneous, mitogen-induced and antigen-specific cytokine production in cynomolgus and rhesus macaques." in: Journal of immunological methods, Vol. 270, Issue 1, pp. 85-97, (2002) (PubMed).

Details zu GM-CSF

Target: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Andere Bezeichnung: GMCSF

Gen-ID: 1437

Pathways: JAK-STAT Signalweg, Cellular Response to Molecule of Bacterial Origin