IL-2 Antikörper

Produktnummer ABIN6963857

Dieses Maus Monoklonal-Antikörper erkennt spezifisch IL-2 in ELISA und ELISpot. Er zeigt eine Reaktivität gegenüber Human und Non-Human Primate und wurde in 4+ Publikationen erwähnt.

Kurzübersicht für IL-2 Antikörper (ABIN6963857)

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Reaktivität: Human, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser IL-2 Antikörper ist unkonjugiert

Applikation: ELISA, ELISpot

Klon: MT2A91-2C95

Produktdetails anti-IL-2 Antikörper

Spezifität: Native and recombinant IL-2

Kreuzreaktivität (Details): The monoclonal antibodies cross-react with IL-2 from non-human primates.

Produktmerkmale: These monoclonal antibodies enable specific detection of human IL-2 in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples

Aufreinigung: Purified from in vitro cultures by protein G affinity chromatography.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant human IL-2

Isotyp: IgG1, IgG2b

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

ABIN6963855 and ABIN6963856/2C95 are recommended as capture mAbs in ELISpot, FluoroSpot, and ELISA in combination with detection mAb ABIN6963858, ABIN7448302 and ABIN6963859 .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store product at 4-8°C.

Haltbarkeit: 18 months

Referenzen für anti-IL-2 Antikörper (ABIN6963857)

Starc, Li, Algeri, Conforti, Tomao, Pitisci, Emma, Montini, Messa, Locatelli, Bernardo, Vivarelli: "Phenotypic and functional characterization of mesenchymal stromal cells isolated from pediatric patients with severe idiopathic nephrotic syndrome." in: Cytotherapy, Vol. 20, Issue 3, pp. 322-334, (2019) (PubMed).

Ashrafi, Shapouri, Mahdavi: "Immunological consequences of immunization with tumor lysate vaccine and propranolol as an adjuvant: A study on cytokine profiles in breast tumor microenvironment." in: Immunology letters, Vol. 181, pp. 63-70, (2017) (PubMed).

Douthwaite, Moisan, Privezentzev, Soskic, Sabbah, Cohen, Collinson, England, Huntington, Kemp, Zhuang, Hudak, Rees, Goldberg, Barton, Chang, Vainshtein, Liang, Iciek, Ambery, Peakman, Vaughan, Tree et al.: "A CD80-Biased CTLA4-Ig Fusion Protein with Superior In Vivo Efficacy by Simultaneous Engineering of Affinity, Selectivity, Stability, and FcRn Binding. ..." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 198, Issue 1, pp. 528-537, (2017) (PubMed).

Forghieri, Luppi, Barozzi, Riva, Morselli, Bigliardi, Quadrelli, Vallerini, Maccaferri, Coluccio, Paolini, Colaci, Bonacorsi, Maiorana, Tagliazucchi, Rumpianesi, Mattioli, Presutti, Gelmini, Cermelli et al.: "Chronic and recurrent benign lymphadenopathy without constitutional symptoms associated with human herpesvirus-6B reactivation. ..." in: British journal of haematology, Vol. 172, Issue 4, pp. 561-72, (2016) (PubMed).

Details zu IL-2

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Andere Bezeichnung: IL2

Gen-ID: 3558

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation