Interferon gamma Antikörper (Alkaline Phosphatase (AP))

Produktnummer ABIN6963840

Der Maus Monoklonal Anti-Interferon gamma-Antikörper wurde für ELISpot validiert. Er ist geeignet, Interferon gamma in Proben von Human und Non-Human Primate zu detektieren. Es sind 5+ Publikationen verfügbar.

Kurzübersicht für Interferon gamma Antikörper (Alkaline Phosphatase (AP)) (ABIN6963840)

Target: Interferon gamma (IFNG)

Reaktivität: Human, Non-Human Primate

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Interferon gamma Antikörper ist konjugiert mit Alkaline Phosphatase (AP)

Applikation: ELISpot

Klon: 7-B6-1

Produktdetails anti-Interferon gamma Antikörper (Alkaline Phosphatase (AP))

Spezifität: Native and recombinant IFN-γ

Kreuzreaktivität (Details): The monoclonal antibody cross-reacts with IFN-γ from non-human primates.

Aufreinigung: Purified from in vitro cultures by protein G affinity chromatography.

Immunogen: Recombinant human IFN-gamma

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: For enumeration of IFN-γ producing cells using ELISpot. 7-B6-1 is recommended as detection mAb in combination with coating mAb 1-D1K for human IFN-γ .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Lagerung: 4 °C

Informationen zur Lagerung: Store product at 4-8°C.

Haltbarkeit: 18 months

Referenzen für anti-Interferon gamma Antikörper (Alkaline Phosphatase (AP)) (ABIN6963840)

Wentink, Verheul, Griffioen, Schafer, McPherson, Early, van der Vliet, de Gruijl: "A safety and immunogenicity study of immunization with hVEGF26-104/RFASE in cynomolgus monkeys." in: Vaccine, Vol. 36, Issue 15, pp. 2025-2032, (2018) (PubMed).

Ellis, Balgeman, Rodgers, Updike, Tomko, Maiello, Scanga, OConnor: "Characterization of T Cells Specific for CFP-10 and ESAT-6 in Mycobacterium tuberculosis-Infected Mauritian Cynomolgus Macaques." in: Infection and immunity, Vol. 85, Issue 4, (2017) (PubMed).

Sahin, Derhovanessian, Miller, Kloke, Simon, Löwer, Bukur, Tadmor, Luxemburger, Schrörs, Omokoko, Vormehr, Albrecht, Paruzynski, Kuhn, Buck, Heesch, Schreeb, Müller, Ortseifer, Vogler, Godehardt et al.: "Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer. ..." in: Nature, Vol. 547, Issue 7662, pp. 222-226, (2017) (PubMed).

Gubin, Zhang, Schuster, Caron, Ward, Noguchi, Ivanova, Hundal, Arthur, Krebber, Mulder, Toebes, Vesely, Lam, Korman, Allison, Freeman, Sharpe, Pearce, Schumacher, Aebersold, Rammensee, Melief, Mardis et al.: "Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens. ..." in: Nature, Vol. 515, Issue 7528, pp. 577-81, (2015) (PubMed).

Czerkinsky, Andersson, Ekre, Nilsson, Klareskog, Ouchterlony: "Reverse ELISPOT assay for clonal analysis of cytokine production. I. Enumeration of gamma-interferon-secreting cells." in: Journal of immunological methods, Vol. 110, Issue 1, pp. 29-36, (1988) (PubMed).

Details zu Interferon gamma

Target: Interferon gamma (IFNG)

Andere Bezeichnung: IFNG

Gen-ID: 3458

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie