Interferon gamma Antikörper (Biotin)

Produktnummer ABIN6963816

Der Ratte Monoklonal Anti-Interferon gamma-Antikörper wurde für ELISA und ELISpot validiert. Er ist geeignet, Interferon gamma in Proben von Maus zu detektieren. Es sind 4+ Publikationen verfügbar.

Kurzübersicht für Interferon gamma Antikörper (Biotin) (ABIN6963816)

Target: Interferon gamma (IFNG)

Reaktivität: Maus

Wirt: Ratte

Klonalität: Monoklonal

Konjugat: Dieser Interferon gamma Antikörper ist konjugiert mit Biotin

Applikation: ELISA, ELISpot

Klon: R4-6A2

Produktdetails anti-Interferon gamma Antikörper (Biotin)

Spezifität: Native and recombinant mouse IFN-γ

Produktmerkmale: This monoclonal antibody enables specific detection of mouse IFN-γ in immunoassays such as ELISpot, FluoroSpot, and ELISA. Serum/Plasma samples

Aufreinigung: Biotinylated through reaction with a N-hydroxysuccinimide ester of biotin.,Purified from in vitro cultures by protein G affinity chromatography.

Sterilität: 0.2 μm filtered

Immunogen: Native mouse IFN-gamma

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

ABIN6963816, ABIN7448269 and ABIN6964014 is recommended as detection mAb in ELISpot, FluoroSpot, and ELISA in combination with capture mAb ABIN6963815 and ABIN7448268 .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Haltbarkeit: 18 months

Referenzen für anti-Interferon gamma Antikörper (Biotin) (ABIN6963816)

Bourgeois-Daigneault, Roy, Aitken, El Sayes, Martin, Varette, Falls, St-Germain, Pelin, Lichty, Stojdl, Ungerechts, Diallo, Bell: "Neoadjuvant oncolytic virotherapy before surgery sensitizes triple-negative breast cancer to immune checkpoint therapy." in: Science translational medicine, Vol. 10, Issue 422, (2019) (PubMed).

Veglia, Tyurin, Blasi, De Leo, Kossenkov, Donthireddy, To, Schug, Basu, Wang, Ricciotti, DiRusso, Murphy, Vonderheide, Lieberman, Mulligan, Nam, Hockstein, Masters, Guarino, Lin, Nefedova, Black et al.: "Fatty acid transport protein 2 reprograms neutrophils in cancer. ..." in: Nature, Vol. 569, Issue 7754, pp. 73-78, (2019) (PubMed).

Noguera-Ortega, Blanco-Cabra, Rabanal, Sánchez-Chardi, Roldán, Guallar-Garrido, Torrents, Luquin, Julián: "Mycobacteria emulsified in olive oil-in-water trigger a robust immune response in bladder cancer treatment." in: Scientific reports, Vol. 6, pp. 27232, (2018) (PubMed).

Gregor, Wolchok, Ferrone, Buchinshky, Guevara-Patiño, Perales, Mortazavi, Bacich, Heston, Latouche, Sadelain, Allison, Scher, Houghton: "CTLA-4 blockade in combination with xenogeneic DNA vaccines enhances T-cell responses, tumor immunity and autoimmunity to self antigens in animal and cellular model systems." in: Vaccine, Vol. 22, Issue 13-14, pp. 1700-8, (2004) (PubMed).

Details zu Interferon gamma

Target: Interferon gamma (IFNG)

Andere Bezeichnung: IFNG

Gen-ID: 15978

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie