Interferon gamma Antikörper

Produktnummer ABIN6963768

Der Maus Monoklonal Anti-Interferon gamma-Antikörper wurde für ELISA und ELISpot validiert. Er ist geeignet, Interferon gamma in Proben von Pferd und Rhinoceros zu detektieren. Es sind 3+ Publikationen verfügbar.

Kurzübersicht für Interferon gamma Antikörper (ABIN6963768)

Target: Interferon gamma (IFNG)

Reaktivität: Pferd, Rhinoceros

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser Interferon gamma Antikörper ist unkonjugiert

Applikation: ELISA, ELISpot

Klon: MT166

Produktdetails anti-Interferon gamma Antikörper

Spezifität: Native and recombinant IFN-γ

Kreuzreaktivität (Details): The monoclonal antibody cross-reacts with IFN-γ from dog rhinoceros.

Produktmerkmale: This monoclonal antibody enables specific detection of equine IFN-γ in immunoassays such as ELISpot and ELISA. Serum/Plasma samples

Aufreinigung: Purified from in vitro cultures by protein G affinity chromatography.

Sterilität: 0.2 μm filtered

Immunogen: Recombinant equine IFN-gamma

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

ABIN6963762, ABIN7448233, ABIN6963768, ABIN7448239, ABIN6963770 and ABIN6963771 is recommended as capture mAb in ELISpot and ELISA in combination with detection mAb ABIN6963761, ABIN7448232, ABIN6963769 and ABIN7448240 .

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Haltbarkeit: 18 months

Referenzen für anti-Interferon gamma Antikörper (ABIN6963768)

Cywes-Bentley, Rocha, Bordin, Vinacur, Rehman, Zaidi, Meyer, Anthony, Lambert, Vlock, Giguère, Cohen, Pier: "Antibody to Poly-N-acetyl glucosamine provides protection against intracellular pathogens: Mechanism of action and validation in horse foals challenged with Rhodococcus equi." in: PLoS pathogens, Vol. 14, Issue 7, pp. e1007160, (2019) (PubMed).

Hellman, Hjertner, Morein, Fossum: "The adjuvant G3 promotes a Th1 polarizing innate immune response in equine PBMC." in: Veterinary research, Vol. 49, Issue 1, pp. 108, (2018) (PubMed).

Rocha, Cohen, Bordin, Brake, Giguère, Coleman, Alaniz, Lawhon, Mwangi, Pillai: "Oral Administration of Electron-Beam Inactivated Rhodococcus equi Failed to Protect Foals against Intrabronchial Infection with Live, Virulent R. equi." in: PLoS ONE, Vol. 11, Issue 2, pp. e0148111, (2016) (PubMed).

Details zu Interferon gamma

Target: Interferon gamma (IFNG)

Andere Bezeichnung: IFNG

Gen-ID: 100034181

Pathways: Interferon-gamma Pathway, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagie