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TCR beta Antikörper

TCR beta Reaktivität: Maus FACS, IP, IF, IHC (fro) Wirt: Armenischer Hamster Monoclonal H57-597 unconjugated
Produktnummer ABIN6961770
  • Target Alle TCR beta Antikörper anzeigen
    TCR beta (T Cell Receptor (TCR) beta (TCR beta))
    Reaktivität
    • 44
    • 15
    Maus
    Wirt
    • 24
    • 20
    • 11
    • 4
    Armenischer Hamster
    Klonalität
    • 48
    • 11
    Monoklonal
    Konjugat
    • 15
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TCR beta Antikörper ist unkonjugiert
    Applikation
    • 47
    • 14
    • 10
    • 8
    • 7
    • 6
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Aufreinigung
    This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.
    Klon
    H57-597
    Isotyp
    IgG
    Top Product
    Discover our top product TCR beta Primärantikörper
  • Applikationshinweise
    This purified format is guaranteed to be >90 % pure as determined by SDS-PAGE analysis.
    Kommentare

    0.5 mg/mL

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, pH 7.2
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C
    Informationen zur Lagerung
    2-8°C
    Haltbarkeit
    12 months
  • Target
    TCR beta (T Cell Receptor (TCR) beta (TCR beta))
    Andere Bezeichnung
    TCR beta (TCR beta Produkte)
    Synonyme
    TCRbeta antikoerper, Tib antikoerper, T cell receptor beta chain antikoerper, Tcrb antikoerper
    Hintergrund
    The H57-597 antibody is specific for the beta chain of the mouse T cell Receptor (TCR). This cell surface protein combines with a second protein chain (alpha chain) to form the alpha-beta TCR that is expressed by NK1.1+ thymocytes, NKT cells, and the majority of peripheral T cells. A small number of T cells may express an alternative heteromer of gamma and delta protein chains, known as the gamma-delta TCR. These receptors participate in a complex with CD3, and with the co-receptors CD4 or CD8, to recognize and respond to antigens bound to MHC molecules on antigen-presenting cells. Such interactions promote T cell receptor signaling (T cell activation) and can re- sult in a number of cellular responses including proliferation, differentiation, production of cytokines or activation-induced cell death.The H57-597 antibody is used as a phenotypic marker for T cells expressing the alpha-beta TCR. It is also widely used to cross-link surface TCR and thereby mimic TCR-mediated cell activation or induction of apoptosis. The antibody does not cross-react with cells expressing the gamma-delta TCR.
    Gen-ID
    21577
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