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CD80 Antikörper

CD80 Reaktivität: Maus FACS, IP, IF, IHC (fro), Func Wirt: Armenischer Hamster Monoclonal 16-10A1 unconjugated
Produktnummer ABIN6961450
  • Target Alle CD80 Antikörper anzeigen
    CD80
    Reaktivität
    • 138
    • 107
    • 44
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    Maus
    Wirt
    • 87
    • 71
    • 22
    • 18
    • 17
    • 1
    • 1
    Armenischer Hamster
    Klonalität
    • 137
    • 77
    • 2
    Monoklonal
    Konjugat
    • 85
    • 18
    • 17
    • 15
    • 13
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD80 Antikörper ist unkonjugiert
    Applikation
    • 127
    • 93
    • 69
    • 34
    • 34
    • 21
    • 14
    • 13
    • 13
    • 12
    • 11
    • 11
    • 9
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunoprecipitation (IP), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
    Aufreinigung
    This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.
    Endotoxin-Niveau
    Low endotoxin: < 0.01 EU/ug
    Klon
    16-10A1
    Isotyp
    IgG
    Top Product
    Discover our top product CD80 Primärantikörper
  • Applikationshinweise
    This purified format is guaranteed to be >90 % pure as determined by SDS-PAGE analysis.
    Kommentare

    2.0 mg/mL

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    10 mM NaH2PO4, 150 mM NaCl, pH 7.2
    Konservierungsmittel
    Azide free
    Lagerung
    4 °C
    Informationen zur Lagerung
    2-8°C
    Haltbarkeit
    12 months
  • Target
    CD80
    Andere Bezeichnung
    CD80 (B7-1) (CD80 Produkte)
    Synonyme
    B7 antikoerper, B7-1 antikoerper, B7.1 antikoerper, BB1 antikoerper, CD28LG antikoerper, CD28LG1 antikoerper, LAB7 antikoerper, B71 antikoerper, Cd28l antikoerper, Ly-53 antikoerper, Ly53 antikoerper, MIC17 antikoerper, TSA1 antikoerper, CD80 molecule antikoerper, Cd80 molecule antikoerper, CD80 antigen antikoerper, CD80 antikoerper, Cd80 antikoerper
    Hintergrund
    The 16-10A1 antibody reacts with mouse CD80, also known as B7-1, a 55 kDa type I transmembrane protein ligand for CD152 (CTLA-4) and for CD28, a co- stimulatory receptor for the T cell receptor (TCR). CD28 also binds a second B7 ligand known as CD86 (B7-2). Both CD80 and CD86 are expressed on activated B cells and antigen-presenting cells. These ligands trigger CD28 signaling in concert with TCR activation to drive T cell proliferation, induce high-level expression of IL-2, impart resistance to apoptosis, and enhance T cell cytotoxicity. The interaction / co-stimulatory signaling between the B7 ligands and CD28 or CTLA-4 provides crucial communication between T cells and B cells or APCs to coordinate the adaptive immune response.
    Gen-ID
    12519
    UniProt
    Q00609
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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