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IL7R Antikörper (APC)

Der Ratte Monoklonal Anti-IL7R-Antikörper wurde für FACS validiert. Er ist geeignet, IL7R in Proben von Maus zu detektieren.
Produktnummer ABIN7278008

Kurzübersicht für IL7R Antikörper (APC) (ABIN7278008)

Target

Alle IL7R Antikörper anzeigen
IL7R (Interleukin 7 Receptor (IL7R))

Reaktivität

  • 148
  • 69
  • 29
  • 7
  • 4
  • 2
  • 1
Maus

Wirt

  • 89
  • 69
  • 45
  • 3
  • 1
  • 1
Ratte

Klonalität

  • 118
  • 86
  • 3
Monoklonal

Konjugat

  • 96
  • 16
  • 12
  • 10
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser IL7R Antikörper ist konjugiert mit APC

Applikation

  • 114
  • 102
  • 51
  • 40
  • 29
  • 26
  • 26
  • 21
  • 11
  • 11
  • 7
  • 7
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Flow Cytometry (FACS)

Klon

A7R34
  • Aufreinigung

    This monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation. It is recommended to store the product undiluted at 4°C, and protected from prolonged exposure to light. Do not freeze.

    Isotyp

    IgG2a kappa
  • Applikationshinweise

    This antibody preparation has been quality-tested for flow cytometry using mouse spleen cells, or an appropriate cell type (where indi- cated). The amount of antibody required for optimal staining of a cell sample should be determined empirically in your system.

    Kommentare

    0.2 mg/mL

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Buffer

    10 mM NaH2PO4, 150 mM NaCl, 0.09 % Sodium azide, 0.1 % gelatin, pH 7.2

    Konservierungsmittel

    Sodium azide

    Vorsichtsmaßnahmen

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    4 °C

    Informationen zur Lagerung

    2-8°C protected from light

    Haltbarkeit

    12 months
  • Target

    IL7R (Interleukin 7 Receptor (IL7R))

    Andere Bezeichnung

    CD127 (IL-7Ra)

    Hintergrund

    The A7R34 antibody is specific for mouse CD127, a 60-90 kDa cell surface protein also known as the Interleukin-7 Receptor alpha chain, or IL-7R alpha. CD127 is typically expressed at the cell surface as a heterodimer with the common gamma chain (CD132). This complex acts as the functional receptor for IL-7, a cytokine important in T and B cell development, and in mature T cell homeostasis. A second cytokine known as Thymic Stromal Lymphopoietin (TSLP) also binds to a receptor complex of CD127 and the TSLPR chain to trigger activation of dendritic cells, and is involved in B cell development, allergy and autoimmunity.The A7R34 antibody may be used as a phenotypic marker for CD127 on immature B cells, on subsets of thymocytes which are double negative (CD4-CD8- ) or single positive (CD4+ or CD8+), and at low levels on mature, peripheral T cells. CD127 is a key marker, when used in combination with CD4 and CD25, to distinguish Treg and effector/memory Treg populations known as T(REM).

    Gen-ID

    16172

    UniProt

    P16872

    Pathways

    JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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