SARS-CoV-2 Spike S1 Antikörper (RBD)
Kurzübersicht für SARS-CoV-2 Spike S1 Antikörper (RBD) (ABIN6952746)
Target
Alle SARS-CoV-2 Spike S1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- RBD
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Verwendungszweck
- Polyclonal Rabbit antibody against SARS-CoV-2 (COVID-19) Spike Protein S1 Receptor Binding Domain
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Spezifität
- This antibody was selected for its ability to bind to the virus SARS-CoV-2 Spike Protein Receptor Binding Domain (RBD) from the disease COVID-19.
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Produktmerkmale
- Rabbit anti-SARS-CoV-2 S1 RBD antibody
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Aufreinigung
- The IgG fraction was purified by Protein A affinity chromatography.
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Immunogen
- This antibody was produced from antiserum of rabbits immunized with a recombinant SARS-CoV-2 S1 RBD protein.
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Isotyp
- IgG
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Applikationshinweise
- ELISA (recommended work dilution = 1:160,000)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Lyophilized
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Rekonstitution
- Reconstitute the antibody with sterile water to a final concentration of 1 mg/mL.
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Buffer
- Product is supplied as a powder obtained from lyophilization of purified antibody in citric acid solution.
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Handhabung
- Please avoid freeze-thaw cycles, as this will lower the activity of the antibody.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at 4°C if intended for use within one month, otherwise, store at -20°C to -80°C. The lyophilized antibody is stable for at least 18 months after the date of receipt when stored at -20°C to -80°C. After reconstitution, it can be aliquoted and stored frozen at -20°C to -80°C in a manual defrost freezer for at least 6 months without detectable loss of activity. Upon reconstitution, the antibody can also be stored for 1 month at 4°C.
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Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry. ..." in: Molecular therapy : the journal of the American Society of Gene Therapy, (2021) (PubMed).
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Nanoluciferase complementation-based bioreporter reveals the importance of N-linked glycosylation of SARS-CoV-2 S for viral entry. ..." in: Molecular therapy : the journal of the American Society of Gene Therapy, (2021) (PubMed).
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- SARS-CoV-2 Spike S1
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Substanzklasse
- Viral Protein
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Hintergrund
- It's been reported that 2019-nCoV (COVID-19) can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
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Gen-ID
- 43740568
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UniProt
- P0DTC2
Target
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