KDM4A Antikörper (C-Term)
Kurzübersicht für KDM4A Antikörper (C-Term) (ABIN6952408)
Target
Alle KDM4A Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Güteklasse
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Bindungsspezifität
- C-Term
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Spezifität
- Polyclonal antibody raised in rabbit against human JMJD2a (Jumonji domain containing 2a), using a synthetic peptide containing a sequence from the C-terminal part of the protein.
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Kreuzreaktivität
- Maus
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Aufreinigung
- Affinity purified
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Immunogen
- synthetic peptide
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Applikationshinweise
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ChIP 5 μg:ChIP
WB 1:500
IP 3 μg:IP -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 μg/μL
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Buffer
- TBS, 0,1 % BSA, 0.05 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
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Andere Bezeichnung
- JMJD2a
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Hintergrund
- JMJD2a (UniProtKB/Swiss-Prot entry O75164), belongs to the JMJD2 family of histone demethylases which play an important role in the establishment of the histone code. JMJD2a specifically demethylates the trimethylated K9 and K36 of histone H3, thereby converting these lysines to the dimethylated form. It has no activity towards H3K4, H3K27 and H4K20, or to the mono- and dimethylated H3K9 and H3K36. JMJD2a plays a role in the transcriptional repression of ASCL2 and E2F-responsive promoters via the recruitment of histone deacetylases and NCOR1, respectively.
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UniProt
- O75164
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Pathways
- Warburg Effekt
Target
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