KDM5C Antikörper
Kurzübersicht für KDM5C Antikörper (ABIN6952407)
Target
Alle KDM5C Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Spezifität
- Polyclonal antibody raised in rabbit against human JARID1C (Jumonji, AT Rich Interactive Domain 1C), using a synthetic peptide containing a sequence from the central part of the protein
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Kreuzreaktivität
- Maus
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Aufreinigung
- Affinity purified
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Immunogen
- synthetic peptide
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Applikationshinweise
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ChIP/ChIP-seq 5 μg:ChIP
WB 1:1,000
IP 6 μg:IP -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.2 μg/μL
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Buffer
- TBS, 0,1 % BSA, 0.05 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- KDM5C (Lysine (K)-Specific Demethylase 5C (KDM5C))
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Andere Bezeichnung
- JARID1C
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Hintergrund
- JARID1C (UniProtKB/Swiss-Prot entry P41229) is a histone demethylase that specifically demethylates tri- and dimethylated Lys-4 of histone H3. It has no activity towards monomethylated H3K4, H3K9, H3K27, H3K36, H3K79 or H4K20. It is involved in transcriptional regulation and chromatin remodeling. JARID1C participates in transcriptional repression of neuronal genes by recruiting histone deacetylases and REST at neuron-restrictive silencer elements. Mutations in JARID1C have been associated with X-linked mental retardation
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UniProt
- P41229
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Pathways
- Warburg Effekt
Target
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