Der Maus Monoklonal Anti-POLR2A/RPB1-Antikörper wurde für WB, ChIP und ChIP-seq validiert. Er ist geeignet, POLR2A/RPB1 in Proben von Human zu detektieren.
Produktnummer ABIN6952401
Kurzübersicht für POLR2A/RPB1 Antikörper (ABIN6952401)
Monoclonal antibody raised in mouse against the B1 subunit of RNA polymerase II (polymerase (RNA) II (DNA directed) polypeptide A) of wheat germ. Interacts with the highly conserved C-terminal domain of the protein containing the YSPTSPS repeat.
POLR2A
Reaktivität: Human
IHC, IF, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
ChIP/ChIP-seq 2 μL:ChIP WB 1:500
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
ascites fluid, 0.05 % azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Target
POLR2A/RPB1 (POLR2A)
(RNA Polymerase II Subunit RPB1 (POLR2A))
Andere Bezeichnung
Pol II
Hintergrund
RNA polymerase II (pol II) is a key enzyme in the regulation and control of gene transcription. It is able to unwind the DNA double helix, synthesize RNA, and proofread the result. Pol II is a complex enzyme, consisting of 12 subunits, of which the B1 subunit (UniProt/Swiss-Prot entry P24928) is the largest. Together with the second largest subunit, B1 forms the catalytic core of the RNA polymerase II transcription machinery.