HDAC6 Antikörper (N-Term)
Kurzübersicht für HDAC6 Antikörper (N-Term) (ABIN6952383)
Target
Alle HDAC6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- Polyclonal antibody raised in rabbit against human HDAC6 (Histone deacetylase 6), using two KLH-conjugated synthetic peptides from the N-terminal and the central part of the protein, respectively.
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Aufreinigung
- Peptide affinity purified
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Immunogen
- synthetic peptide
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Applikationshinweise
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ChIP/ChIP-seq 3 μg:ChIP
ELISA 1:1,000
WB not recommended -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.5 μg/μL
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Buffer
- PBS, 0.05 % azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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- HDAC6 (Histone Deacetylase 6 (HDAC6))
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Andere Bezeichnung
- HDAC6
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Hintergrund
- HDAC6 (UniProt/Swiss-Prot entry Q9UBN7) belongs to class II of the histone deacetylase family. These enzymes catalyse the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation plays an important role in transcriptional regulation, cell cycle progression and developmental events. HDAC6 also plays a key role in the degradation of misfolded proteins and in microtubule-dependent cell motility via deacetylation of tubulin and is involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
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UniProt
- Q9UBN7
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
Target
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