Der Kaninchen Polyklonal Anti-HDAC6-Antikörper wurde für ELISA, ChIP und ChIP-seq validiert. Er ist geeignet, HDAC6 in Proben von Human zu detektieren.
Produktnummer ABIN6952383
Kurzübersicht für HDAC6 Antikörper (N-Term) (ABIN6952383)
Polyclonal antibody raised in rabbit against human HDAC6 (Histone deacetylase 6), using two KLH-conjugated synthetic peptides from the N-terminal and the central part of the protein, respectively.
HDAC6
Reaktivität: Human
ELISA, FACS
Wirt: Maus
Monoclonal
4G6F9
unconjugated
Applikationshinweise
ChIP/ChIP-seq 3 μg:ChIP ELISA 1:1,000 WB not recommended
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.5 μg/μL
Buffer
PBS, 0.05 % azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Target
HDAC6
(Histone Deacetylase 6 (HDAC6))
Andere Bezeichnung
HDAC6
Hintergrund
HDAC6 (UniProt/Swiss-Prot entry Q9UBN7) belongs to class II of the histone deacetylase family. These enzymes catalyse the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation plays an important role in transcriptional regulation, cell cycle progression and developmental events. HDAC6 also plays a key role in the degradation of misfolded proteins and in microtubule-dependent cell motility via deacetylation of tubulin and is involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.