Polyclonal antibody raised in rabbit against human FOXA2 (Forkhead Box A2), using two synthetic peptides containing a sequence from the central part and the N-terminus of the protein, respectively.
FOXA2
Reaktivität: Human
WB, IF, IP
Wirt: Kaninchen
Monoclonal
unconjugated
Applikationshinweise
ChIP/ChIP-seq 2 μg:ChIP ELISA 1:5,000 WB 1:500
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
2.4 μg/μL
Buffer
PBS, 0.05 % azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Target
FOXA2
(Forkhead Box A2 (FOXA2))
Andere Bezeichnung
FOXA2
Hintergrund
FOXA2 (UniProtKB/Swiss-Prot entry Q9Y261) is a member of the forkhead class of transcription factors which are involved in the transcriptional activation of liver-specific genes such as AFP, albumin, tyrosine aminotransferase, PEPCK and transthyretin. FOXA2 also plays a role glucose homeostasis and in the regulation of fat metabolism and is required for the embryonic development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs. The FOXA2 gene has been linked to sporadic cases of maturity-onset diabetes of the young.