STING/TMEM173 Antikörper
-
- Target Alle STING/TMEM173 (TMEM173) Antikörper anzeigen
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser STING/TMEM173 Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Flow Cytometry (FACS)
- Kreuzreaktivität
- Human
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Recombinant protein within human TMEM173 aa 200 to the C-terminus
- Klon
- 1B8
- Isotyp
- IgG
- Top Product
- Discover our top product TMEM173 Primärantikörper
-
-
- Applikationshinweise
-
WB 1:300-5000
FCM 1:20-100 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- STING/TMEM173 (TMEM173) (Transmembrane Protein 173 (TMEM173))
- Andere Bezeichnung
- TMEM173 (TMEM173 Produkte)
- Synonyme
- ERIS antikoerper, MITA antikoerper, MPYS antikoerper, NET23 antikoerper, STING antikoerper, 2610307O08Rik antikoerper, Mita antikoerper, RGD1562552 antikoerper, transmembrane protein 173 antikoerper, TMEM173 antikoerper, Tmem173 antikoerper
- Hintergrund
-
Synonyms: Stimulator of interferon genes protein, Endoplasmic reticulum interferon stimulator, Mediator of IRF3 activation, Transmembrane protein 173, hSTING, ERIS, hMITA, TMEM173, ERIS, MITA, STING.
Background: Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent anti-viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway.
- Gen-ID
- 340061
- UniProt
- Q86WV6
- Pathways
- Activation of Innate immune Response
-