Reelin Antikörper (AA 241-340)
Kurzübersicht für Reelin Antikörper (AA 241-340) (ABIN6944773)
Target
Alle Reelin (RELN) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 241-340
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Verwendungszweck
- Reelin Recombinant Antibody
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Kreuzreaktivität
- Human, Ratte
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Aufreinigung
- Purified by Protein A.
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Immunogen
- Human Reelin aa 241-340
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Isotyp
- IgG
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Applikationshinweise
- WB(WB=1:500-2000)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- Reelin (RELN)
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Andere Bezeichnung
- Reelin
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Hintergrund
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Synonyms: Reelin, RELN
Background: Extracellular matrix serine protease that plays a role in layering of neurons in the cerebral cortex and cerebellum. Regulates microtubule function in neurons and neuronal migration. Affects migration of sympathetic preganglionic neurons in the spinal cord, where it seems to act as a barrier to neuronal migration. Enzymatic activity is important for the modulation of cell adhesion. Binding to the extracellular domains of lipoprotein receptors VLDLR and LRP8/APOER2 induces tyrosine phosphorylation of DAB1 and modulation of TAU phosphorylation.
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Gen-ID
- 5649
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UniProt
- P78509
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Pathways
- Synaptic Membrane
Target
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