PEN2 Antikörper
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- Target Alle PEN2 (PSENEN) Antikörper anzeigen
- PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser PEN2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Synthetic peptide corresponding to C-terminal human PEN2.
- Klon
- 1D8
- Isotyp
- IgG
- Top Product
- Discover our top product PSENEN Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C for 12 months.
- Haltbarkeit
- 12 months
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- Target
- PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
- Andere Bezeichnung
- PSENEN (PSENEN Produkte)
- Hintergrund
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Synonyms: Gamma-secretase subunit PEN-2, Presenilin enhancer protein 2, PSENEN, PEN2, presenilin enhancer gamma-secretase subunit, MDS033
Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.
- Gen-ID
- 55851
- UniProt
- Q9NZ42
- Pathways
- Notch Signalweg, Neurotrophin Signalübertragung
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