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PEN2 Antikörper

PSENEN Reaktivität: Human, Maus, Ratte WB, IF (cc), IF (p), IHC (p), FACS Wirt: Kaninchen Monoclonal 1D8 unconjugated
Produktnummer ABIN6944688
  • Target Alle PEN2 (PSENEN) Antikörper anzeigen
    PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
    Reaktivität
    • 33
    • 32
    • 26
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 38
    • 3
    Kaninchen
    Klonalität
    • 30
    • 11
    Monoklonal
    Konjugat
    • 17
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PEN2 Antikörper ist unkonjugiert
    Applikation
    • 29
    • 13
    • 13
    • 11
    • 5
    • 5
    • 3
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    Synthetic peptide corresponding to C-terminal human PEN2.
    Klon
    1D8
    Isotyp
    IgG
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  • Applikationshinweise
    WB 1:300-5000
    FCM 1:20-100
    IHC-P 1:200-400
    IF(IHC-P) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C for 12 months.
    Haltbarkeit
    12 months
  • Target
    PEN2 (PSENEN) (Presenilin Enhancer 2 Homolog (PSENEN))
    Andere Bezeichnung
    PSENEN (PSENEN Produkte)
    Hintergrund

    Synonyms: Gamma-secretase subunit PEN-2, Presenilin enhancer protein 2, PSENEN, PEN2, presenilin enhancer gamma-secretase subunit, MDS033

    Background: Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Probably represents the last step of maturation of gamma-secretase, facilitating endoproteolysis of presenilin and conferring gamma-secretase activity.

    Gen-ID
    55851
    UniProt
    Q9NZ42
    Pathways
    Notch Signalweg, Neurotrophin Signalübertragung
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