PDGFRA Antikörper (pTyr720) (HRP)

Produktnummer ABIN6944467

Der Kaninchen Polyklonal Anti-PDGFRA-Antikörper wurde für WB und ELISA validiert. Er ist geeignet, PDGFRA in Proben von Human zu detektieren.

Kurzübersicht für PDGFRA Antikörper (pTyr720) (HRP) (ABIN6944467)

Target: PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDGFRA Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-PDGFRA Antikörper (HRP)

Bindungsspezifität: pTyr720

Kreuzreaktivität: Human

Homologie: Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthesised phosphopeptide derived from human PDGFRA around the phosphorylation site of Tyr720

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PDGFRA

Target: PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

Andere Bezeichnung: PDGFRA

Hintergrund:

Synonyms: PDGF Receptor alpha (phospho Y720), p-PDGF Receptor alpha (phospho Y720), Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, CD140a, CD140a antigen, MGC74795, PDGF alpha chain, PDGF-R-alpha, PDGFR 2, PDGFR alpha, PDGFR2, PDGFRA, PDGFRA/BCR fusion, PGFRA_HUMAN, Platelet derived growth factor receptor 2, Platelet derived growth factor receptor alpha, Platelet derived growth factor receptor alpha polypeptide, Platelet derived growth factor receptor, Rearranged in hypereosinophilia platelet derived growth factor receptor alpha fusion protein, RHEPDGFRA.

Background: This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies suggest that this gene plays a role in organ development, wound healing, and tumor progression. Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a variety of other cancers. [provided by RefSeq, Mar 2012]

Gen-ID: 5156

UniProt: P16234

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Platelet-derived growth Factor Receptor Signaling