ORC2 Antikörper
Kurzübersicht für ORC2 Antikörper (ABIN6944371)
Target
Alle ORC2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Kreuzreaktivität
- Human
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Aufreinigung
- Protein G purified monoclonal antibody in PBS containing 0.05% azide.
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Immunogen
- Monoclonal antibody raised in mouse against human ORC2, using two recombinant proteins containing the N-terminal and C-terminal part of the protein, respectively
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Isotyp
- IgG1
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Applikationshinweise
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WB 1:300-5000
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 0.6 μg/μL
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Buffer
- PBS with 0.05 % sodium azide.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C for 12 months.
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Haltbarkeit
- 12 months
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- ORC2 (Origin Recognition Complex Subunit 2 (ORC2))
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Andere Bezeichnung
- ORC2
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Hintergrund
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Synonyms: ORC2L, Origin recognition complex subunit 2, ORC2
Background: Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3. Stabilizes LRWD1, by protecting it from ubiquitin-mediated proteasomal degradation. Also stabilizes ORC3.
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Gen-ID
- 4999
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UniProt
- Q13416
Target
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