Nesprin3 Antikörper (AA 201-300) (HRP)
-
- Target Alle Nesprin3 (C14orf49) Antikörper anzeigen
- Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))
-
Bindungsspezifität
- AA 201-300
-
Reaktivität
- Human, Maus, Ratte
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser Nesprin3 Antikörper ist konjugiert mit HRP
-
Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Kreuzreaktivität
- Human, Maus, Ratte
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human Nesprin 3
- Isotyp
- IgG
- Top Product
- Discover our top product C14orf49 Primärantikörper
-
-
- Applikationshinweise
-
WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))
- Andere Bezeichnung
- Nesprin 3 (C14orf49 Produkte)
- Hintergrund
-
Synonyms: C14orf49, Chromosome 14 open reading frame 49, FLJ25605, MGC75267, Nesp3, Nesprin3, Nesprin-3, NET53, Nuclear Envelope Spectrin Repeat Protein 3, Spectrin Repeat Containing, Nuclear Envelope Family Member 3, SYNE3, SYNE3_HUMAN.
Background: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells
- Gen-ID
- 161176
- UniProt
- Q6ZMZ3
- Pathways
- Maintenance of Protein Location
-