Nesprin3 Antikörper (AA 740-920)

Produktnummer ABIN6148766

Produktdetails anti-Nesprin3 Antikörper

Target: Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))

Bindungsspezifität: AA 740-920

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nesprin3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF)

Sequenz: LRLLEESLLS LIRNWHLQRM EVDSGKKMVF TNNIPKSGFL INPMDPIPRH RRRANLLQEE EGSHEDFSQL LRNFGQWLQV ENSKLVRIIA MRTSTAEDLR TRKSKLQELE ARVPEGQHLF ENLLRLGPAR GTSDELEDLR YQWMLYKSKL KDSGHLLTQS SPGEPTGFQK TRRWRGLGSL F

Kreuzreaktivität: Human, Maus

Produktmerkmale: Polyclonal Antibodies

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 740-920 of human SYNE3 (NP_689805.3).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IF,1:50 - 1:200

Kommentare:

HIGH QUALITY

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Nesprin3

Target: Nesprin3 (C14orf49) (Chromosome 14 Open Reading Frame 49 (C14orf49))

Andere Bezeichnung: SYNE3 (C14orf49 Produkte)

Synonyme: C14orf49 antikoerper, NET53 antikoerper, Nesp3 antikoerper, 4831426I19Rik antikoerper, nesprin-3 antikoerper, spectrin repeat containing nuclear envelope family member 3 antikoerper, spectrin repeat containing, nuclear envelope family member 3 antikoerper, SYNE3 antikoerper, Syne3 antikoerper

Hintergrund: As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.,SYNE3,C14orf139,C14orf49,KASH3,LINC00341,NCRNA00341,NET53,Nesp3,nesprin-3,Signal Transduction,Cell Biology & Developmental Biology,Cytoskeleton,Microfilaments,SYNE3

Molekulargewicht: 68 kDa/111 kDa/112 kDa

Gen-ID: 161176

UniProt: Q6ZMZ3

Pathways: Maintenance of Protein Location