Rekombinanter MMP14 Antikörper (AA 150-250)
Kurzübersicht für Rekombinanter MMP14 Antikörper (AA 150-250) (ABIN6944106)
Target
Alle MMP14 Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- AA 150-250
-
Verwendungszweck
- MMP14 Recombinant Antibody
-
Kreuzreaktivität
- Human, Maus, Ratte
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- Recombinant human MMP14 between 150 to 250 amino acids
-
Isotyp
- IgG
-
-
-
-
Applikationshinweise
- WB(1:500-2000), IHC-P(1:50-100), IHC-F(1:100-500), IP(1-2 μg), IF(), Flow-Cyt(1 μg/Test), ICC/IF(1:50-100)
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- 4 °C,-20 °C
-
Informationen zur Lagerung
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
-
Haltbarkeit
- 12 months
-
-
- MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
-
Andere Bezeichnung
- MMP14
-
Hintergrund
-
Synonyms: Matrix metalloproteinase-14, MMP-X1, Membrane-type matrix metalloproteinase 1, Membrane-type-1 matrix metalloproteinase, MMP-14, MTMMP1, MT1-MMP, MT1MMP, MT-MMP 1
Background: Seems to specifically activate progelatinase A. May thus trigger invasion by tumor cells by activating progelatinase A on the tumor cell surface. May be involved in actin cytoskeleton reorganization by cleaving PTK7. Acts as a positive regulator of cell growth and migration via activation of MMP15. Involved in the formation of the fibrovascular tissues in association with pro-MMP2.
-
Gen-ID
- 4323
-
UniProt
- P50281
-
Pathways
- Autophagie
Target
-