Rekombinanter MLKL Antikörper (C-Term)
Kurzübersicht für Rekombinanter MLKL Antikörper (C-Term) (ABIN6944094)
Target
Alle MLKL Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
-
-
Bindungsspezifität
- C-Term
-
Verwendungszweck
- MLKL Recombinant Antibody
-
Kreuzreaktivität
- Human
-
Aufreinigung
- Purified by Protein A.
-
Immunogen
- Human MLKL between 350 to C-terminus
-
Isotyp
- IgG
-
-
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 371-471) antibody
MLKL Reaktivität: Human WB, ELISA, IF, IHC (p) Wirt: Maus Monoclonal 3B2 unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 444-472) antibodyMLKL Reaktivität: Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (AA 1-471) antibodyMLKL Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyKD Validated MLKL Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 23GB2935 unconjugated Recombinant Antibody
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyKD Validated MLKL Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 24GB4615 unconjugated Recombinant Antibody
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyKD Validated MLKL Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 24GB4620 unconjugated Recombinant Antibody
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyKD Validated MLKL Reaktivität: Human WB, FACS Wirt: Kaninchen Monoclonal 23GB2895 unconjugated Recombinant Antibody
anti-Mixed Lineage Kinase Domain-Like (MLKL) (pSer347) antibodyMLKL Reaktivität: Human, Maus IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) (pSer358) antibodyMLKL Reaktivität: Human IHC (p) Wirt: Maus Monoclonal 6E3 unconjugated
anti-Mixed Lineage Kinase Domain-Like (MLKL) antibodyMLKL Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
-
-
Applikationshinweise
- WB(WB(1:500-2000))
-
Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
-
-
Format
- Liquid
-
Konzentration
- Lot specific
-
Buffer
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
-
Konservierungsmittel
- ProClin
-
Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Lagerung
- -20 °C
-
Informationen zur Lagerung
- Store at -20°C for 12 months.
-
Haltbarkeit
- 12 months
-
-
- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
-
Andere Bezeichnung
- MLKL
-
Hintergrund
-
Synonyms: Mixed lineage kinase domain-like protein, hMLKL, MLKL
Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity (PubMed:22265413, PubMed:22265414, PubMed:22421439, PubMed:24316671). Binds to highly phosphorylated inositol phosphates such as inositolhexakisphosphate (InsP6) which is essential for its necroptotic function (PubMed:29883610).
-
Gen-ID
- 197259
-
UniProt
- Q8NB16
Target
-
