Rekombinanter MLKL Antikörper (pSer345)
Kurzübersicht für Rekombinanter MLKL Antikörper (pSer345) (ABIN6944093)
Target
Alle MLKL Antikörper anzeigenAntikörpertyp
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- pSer345
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Verwendungszweck
- phospho-MLKL (Ser345) Recombinant Antibody
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Kreuzreaktivität
- Maus
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Aufreinigung
- Purified by Protein A.
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Immunogen
- Synthetic phospho-peptide corresponding to residues surrounding Ser345 of human MLKL
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Isotyp
- IgG
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Applikationshinweise
- WB(1:500-2000), ICC/IF(1:50-200)
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
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Andere Bezeichnung
- MLKL
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Hintergrund
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Synonyms: Phospho-MLKL (S345), pMLKL Ser345, Mixed lineage kinase domain-like protein, Mlkl
Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
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Gen-ID
- 74568
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UniProt
- Q9D2Y4
Target
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