MLKL Antikörper (pSer345)
-
- Target Alle MLKL Antikörper anzeigen
- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
-
Bindungsspezifität
- pSer345
-
Reaktivität
- Maus
-
Wirt
- Kaninchen
-
Klonalität
- Monoklonal
-
Konjugat
- Dieser MLKL Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
- Kreuzreaktivität
- Maus
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Synthetic phospho-peptide corresponding to residues surrounding Ser345 of human MLKL
- Klon
- 7G4
- Isotyp
- IgG
- Top Product
- Discover our top product MLKL Primärantikörper
-
-
- Applikationshinweise
-
WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
-
- Target
- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
- Andere Bezeichnung
- MLKL (MLKL Produkte)
- Synonyme
- MLKL antikoerper, 9130019I15Rik antikoerper, mixed lineage kinase domain like pseudokinase antikoerper, mixed lineage kinase domain-like antikoerper, MLKL antikoerper, mlkl antikoerper, Mlkl antikoerper
- Hintergrund
-
Synonyms: Phospho-MLKL (S345), pMLKL Ser345, Mixed lineage kinase domain-like protein, Mlkl
Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.
- Gen-ID
- 74568
- UniProt
- Q9D2Y4
-