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MLKL Antikörper (pSer345)

MLKL Reaktivität: Maus WB, IHC (p), IF (cc) Wirt: Kaninchen Monoclonal 7G4 unconjugated
Produktnummer ABIN6944093
  • Target Alle MLKL Antikörper anzeigen
    MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
    Bindungsspezifität
    • 12
    • 11
    • 10
    • 8
    • 7
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer345
    Reaktivität
    • 58
    • 40
    • 18
    • 1
    • 1
    Maus
    Wirt
    • 68
    • 8
    Kaninchen
    Klonalität
    • 62
    • 14
    Monoklonal
    Konjugat
    • 34
    • 7
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    Dieser MLKL Antikörper ist unkonjugiert
    Applikation
    • 32
    • 29
    • 15
    • 11
    • 6
    • 5
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Kreuzreaktivität
    Maus
    Aufreinigung
    Purified by Protein A.
    Immunogen
    Synthetic phospho-peptide corresponding to residues surrounding Ser345 of human MLKL
    Klon
    7G4
    Isotyp
    IgG
    Top Product
    Discover our top product MLKL Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    IHC-P 1:200-400
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
    Andere Bezeichnung
    MLKL (MLKL Produkte)
    Synonyme
    MLKL antikoerper, 9130019I15Rik antikoerper, mixed lineage kinase domain like pseudokinase antikoerper, mixed lineage kinase domain-like antikoerper, MLKL antikoerper, mlkl antikoerper, Mlkl antikoerper
    Hintergrund

    Synonyms: Phospho-MLKL (S345), pMLKL Ser345, Mixed lineage kinase domain-like protein, Mlkl

    Background: Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Does not have protein kinase activity.

    Gen-ID
    74568
    UniProt
    Q9D2Y4
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