LIG4 Antikörper
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- Target Alle LIG4 Antikörper anzeigen
- LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Monoklonal
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Konjugat
- Dieser LIG4 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Human
- Aufreinigung
- Purified by Protein A.
- Immunogen
- Recombinant protein within human DNA Ligase IV aa 500-700
- Klon
- 2D9
- Isotyp
- IgG
- Top Product
- Discover our top product LIG4 Primärantikörper
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- Applikationshinweise
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WB 1:300-5000
IHC-P 1:200-400 - Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- 4 °C,-20 °C
- Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- LIG4 (Ligase IV, DNA, ATP-Dependent (LIG4))
- Andere Bezeichnung
- LIG4 (LIG4 Produkte)
- Synonyme
- zgc:165595 antikoerper, lig4 antikoerper, DNA LIGASE IV antikoerper, LIG4 antikoerper, lig4-A antikoerper, 5830471N16Rik antikoerper, tiny antikoerper, DNL4 antikoerper, ligase IV, DNA, ATP-dependent antikoerper, DNA ligase 4 antikoerper, ATP-dependent DNA ligase implicated in dsDNA break repair via nonhomologous end-joining antikoerper, DNA ligase IV antikoerper, ligase IV, DNA, ATP-dependent L homeolog antikoerper, lig4 antikoerper, LIG4 antikoerper, LOC100212302 antikoerper, CpipJ_CPIJ005161 antikoerper, PTRG_09982 antikoerper, MCYG_05151 antikoerper, LOC657210 antikoerper, ATLIG4 antikoerper, lig4.L antikoerper, Lig4 antikoerper
- Hintergrund
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Synonyms: DNA ligase 4, DNA ligase IV, Polydeoxyribonucleotide synthase [ATP] 4, LIG4.
Background: Efficiently joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. Involved in DNA non-homologous end joining (NHEJ) required for double-strand break repair and V(D)J recombination. The LIG4-XRCC4 complex is responsible for the NHEJ ligation step, and XRCC4 enhances the joining activity of LIG4. Binding of the LIG4-XRCC4 complex to DNA ends is dependent on the assembly of the DNA-dependent protein kinase complex DNA-PK to these DNA ends.
- Gen-ID
- 3981
- UniProt
- P49917
- Pathways
- DNA Reparatur, Production of Molecular Mediator of Immune Response
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