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KREMEN2 Antikörper (AA 351-450)

KREMEN2 Reaktivität: Maus, Ratte WB, ELISA, IF (cc), IF (p), ICC, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN6943890
  • Target Alle KREMEN2 Antikörper anzeigen
    KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
    Bindungsspezifität
    • 14
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 351-450
    Reaktivität
    • 20
    • 16
    • 15
    Maus, Ratte
    Wirt
    • 31
    • 3
    Kaninchen
    Klonalität
    • 34
    Polyklonal
    Konjugat
    • 10
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser KREMEN2 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 17
    • 12
    • 12
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Kreuzreaktivität
    Maus, Ratte
    Homologie
    Human,Dog,Sheep
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human KREMEN2
    Isotyp
    IgG
    Top Product
    Discover our top product KREMEN2 Primärantikörper
  • Applikationshinweise
    WB 1:300-5000
    ELISA 1:500-1000
    IHC-P 1:200-400
    IHC-F 1:100-500
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    ICC 1:100-500
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    Haltbarkeit
    12 months
  • Target
    KREMEN2 (Kringle Containing Transmembrane Protein 2 (KREMEN2))
    Andere Bezeichnung
    KREMEN2 (KREMEN2 Produkte)
    Synonyme
    krm2 antikoerper, KREMEN2 antikoerper, MGC147633 antikoerper, KRM2 antikoerper, 2900054E04Rik antikoerper, Krm2 antikoerper, kringle containing transmembrane protein 2 S homeolog antikoerper, kringle containing transmembrane protein 2 antikoerper, kremen2.S antikoerper, KREMEN2 antikoerper, kremen2 antikoerper, Kremen2 antikoerper
    Hintergrund

    Synonyms: Dickkopf receptor 2, KREM2_HUMAN, KREMEN 2, Kremen protein 2, Kremen protein 2 precursor, Kremen2, Kringle containing protein marking the eye and the nose, Kringle containing transmembrane protein 2, Kringle domain containing transmembrane protein 2, Kringle domain-containing transmembrane protein 2, Kringle-containing protein marking the eye and the nose, KRM 2, KRM2, MGC10791, MGC16709.

    Background: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

    Gen-ID
    79412
    UniProt
    Q8NCW0
    Pathways
    WNT Signalweg
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