KCTD17 Antikörper (AA 1-100) (FITC)

Produktnummer ABIN6943879

Produktdetails anti-KCTD17 Antikörper (FITC)

Target: KCTD17 (Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))

Bindungsspezifität: AA 1-100

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCTD17 Antikörper ist konjugiert mit FITC

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KCTD17

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu KCTD17

Target: KCTD17 (Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))

Andere Bezeichnung: KCTD17 (KCTD17 Produkte)

Hintergrund:

Synonyms: BTB, BTB/POZ domain-containing protein KCTD17, FLJ12242, FLJ98761, KCD17_HUMAN, KCTD17, Potassium channel tetramerisation domain containing 17, POZ domain-containing protein KCTD17, RP5-1170K4.4.

Background: Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation (PubMed:25270598). May be involved in endoplasmic reticulum calcium ion homeostasis (PubMed:25983243).

Gen-ID: 79734

UniProt: Q8N5Z5