KCTD17 Antikörper (AA 1-100)

Produktnummer ABIN6943866

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch KCTD17 in IF (cc), IF (p), IHC (fro) und IHC (p). Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für KCTD17 Antikörper (AA 1-100) (ABIN6943866)

Target: KCTD17 (Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCTD17 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-KCTD17 Antikörper

Bindungsspezifität: AA 1-100

Verwendungszweck: KCTD17 Polyclonal Antibody

Kreuzreaktivität: Maus, Ratte

Homologie: Human,Cow,Pig

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human KCTD17

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu KCTD17

Target: KCTD17 (Potassium Channel Tetramerisation Domain Containing 17 (KCTD17))

Andere Bezeichnung: KCTD17

Hintergrund:

Synonyms: BTB, BTB/POZ domain-containing protein KCTD17, FLJ12242, FLJ98761, KCD17_HUMAN, KCTD17, Potassium channel tetramerisation domain containing 17, POZ domain-containing protein KCTD17, RP5-1170K4.4.

Background: Is a positive regulator of ciliogenesis, playing a crucial role in the initial steps of axoneme extension. It acts as a substrate-adapter for CUL3-RING ubiquitin ligase complexes which mediate the ubiquitination and subsequent proteasomal degradation of TCHP, a protein involved in ciliogenesis down-regulation (PubMed:25270598). May be involved in endoplasmic reticulum calcium ion homeostasis (PubMed:25983243).

Gen-ID: 79734

UniProt: Q8N5Z5