EXOC1 Antikörper (AA 701-800) (HRP)

Produktnummer ABIN6943328

Dieses Anti-EXOC1-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von EXOC1 in ELISA, IHC (p) und IHC (fro). Geeignet für Ratte.

Kurzübersicht für EXOC1 Antikörper (AA 701-800) (HRP) (ABIN6943328)

Target: EXOC1 (Exocyst Complex Component 1 (EXOC1))

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EXOC1 Antikörper ist konjugiert mit HRP

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-EXOC1 Antikörper (HRP)

Bindungsspezifität: AA 701-800

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human EXOC1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu EXOC1

Target: EXOC1 (Exocyst Complex Component 1 (EXOC1))

Andere Bezeichnung: EXOC1

Hintergrund:

Synonyms: BM-012, exoc1, EXOC1_HUMAN, Exocyst complex component 1, Exocyst complex component Sec3, FLJ10893, SEC3, SEC3 like 1, SEC3L1, SEC3P.

Background: Exocytosis is crucial in membrane trafficking and it mediates hormone and neurotransmitter secretion out of the cell, as well as the incorporation of membrane proteins and lipids to the plasma membrane. It is crucial for cell-cell communication, cell growth and cell polarity. The exocyst complex is a multi-protein complex that consists of Sec3, Sec5, Sec6, Sec8, Sec10, Sec15, Exo70 and Exo84, and is essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Exo70, also known as EXOC7 (exocyst complex component 7), EXOC1 or 2-5-3p, is a 735 amino acid peripheral membrane protein that is a component of the exocyst complex. Localized to the cytoplasm and the cell membrane, Exo70 plays an essential role in the docking of exocystic vesicles to target sites on the plasma membrane and, specifically, may be involved in insulin-induced protein docking within the cell. Four isoforms of Exo70 are expressed due to alternative splicing events.

Gen-ID: 55763

UniProt: Q9NV70

Pathways: Peptide Hormone Metabolism, Synaptic Vesicle Exocytosis