EPOR Antikörper (AA 301-450) (PE)
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- Target
- EPOR (Erythropoietin Receptor (EPOR))
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Bindungsspezifität
- AA 301-450
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Reaktivität
- Human, Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser EPOR Antikörper ist konjugiert mit PE
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Applikation
- Western Blotting (WB)
- Kreuzreaktivität
- Human, Maus, Ratte
- Homologie
- Dog,Cow,Horse
- Aufreinigung
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human EPOR
- Isotyp
- IgG
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- Applikationshinweise
- FCM 1:20-100
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Haltbarkeit
- 12 months
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- Target
- EPOR (Erythropoietin Receptor (EPOR))
- Andere Bezeichnung
- EPOR
- Hintergrund
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Synonyms: EPO-R, Erythropoietin receptor, EPOR
Background: Receptor for erythropoietin. Mediates erythropoietin-induced erythroblast proliferation and differentiation. Upon EPO stimulation, EPOR dimerizes triggering the JAK2/STAT5 signaling cascade. In some cell types, can also activate STAT1 and STAT3. May also activate the LYN tyrosine kinase. Isoform EPOR-T acts as a dominant-negative receptor of EPOR-mediated signaling.
- Gen-ID
- 2057
- UniProt
- P19235
- Pathways
- JAK-STAT Signalweg
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