EGFRviii Antikörper (AA 321-520)
Kurzübersicht für EGFRviii Antikörper (AA 321-520) (ABIN6943225)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 321-520
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Kreuzreaktivität
- Human
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Homologie
- Mouse,Rat,Dog,Sheep,Pig,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human EGFRvIII
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Isotyp
- IgG
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anti-EGFR vIII (EGFRv3) (AA 1-50) antibody
EGFRv3 Reaktivität: Human WB, FACS, IF (cc), IF (p), ELISA, IHC (fro), IHC (p) Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
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WB 1:300-5000
ELISA 1:500-1000 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- 4 °C,-20 °C
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Informationen zur Lagerung
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Haltbarkeit
- 12 months
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- EGFRviii (EGFRv3) (EGFR vIII (EGFRv3))
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Andere Bezeichnung
- EGFRvIII
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Hintergrund
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Synonyms: GFRvIII, Epidermal growth factor receptor variant type _, epidermal growth factor receptor isoform a variant.
Background: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
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Gen-ID
- 1956
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UniProt
- P00533
Target
-
